Mezo and Anchorage Digital: An Institutional Gateway to Bitcoin-Native DeFi

Mezo, a platform specializing in Bitcoin-native Decentralized Finance (DeFi), is advancing its capabilities in Bitcoin-backed lending and yield generation through a strategic partnership with Anchorage Digital. This collaboration aims to provide institutions, including publicly traded companies and digital asset treasuries, with a compliant on-ramp to the world of Bitcoin-based DeFi.

Fixed 1% Interest MUSD Loans

Under this partnership, institutions can leverage Anchorage’s Porto wallet to borrow against their Bitcoin (BTC) holdings at fixed interest rates of 1%. This is facilitated through Mezo’s Bitcoin-backed stablecoin, MUSD. This mechanism enables institutions to manage their liquidity more efficiently while leveraging the value of their Bitcoin assets.

Short-Term veBTC Rewards and Governance Rights

In addition to MUSD loans, Mezo also offers short-term yield-generating tools. Clients can now lock up Bitcoin for periods ranging from 6 to 30 days and receive veBTC in return. These tokens represent shares in on-chain network fees and offer higher rewards for longer commitments, along with governance rights over Mezo’s fee structure and economics.

Realizing Hal Finney's Vision

Matt Luongo, CEO of Thesis and co-founder of Mezo, stated: “Mezo is realizing Hal Finney's vision for a Bitcoin banking experience that issues its own digital currency backed by Bitcoin, acting as banks did before they became nationalized.”

Mezo: A Bitcoin-Native DeFi Protocol

Mezo is a Bitcoin-native DeFi protocol that allows users to borrow, save, and earn yield through on-chain tools powered by MUSD. It was developed by Thesis, a Bitcoin venture studio founded in 2014 specializing in building decentralized products and infrastructure.

Surge in Bitcoin-Backed Lending

Bitcoin-backed lending is experiencing increasing momentum in 2025, with a steady stream of new platforms and products emerging online. This trend is projected to grow sharply, with a February report from Osler, Hoskin & Harcourt estimating that the market could surge to $45 billion by 2030.

Other Expansions in the Bitcoin Lending Market

Tether recently disclosed its acquisition of an undisclosed stake in Ledn, a Bitcoin-backed lending platform providing consumer loans secured by cryptocurrencies. In October, Ledn reported originating $392 million in Bitcoin-backed loans during the third quarter of 2025. In May, Cantor Fitzgerald collaborated with Maple Finance and FalconX to execute its inaugural loan backed by Bitcoin, underscoring Wall Street’s increasing interest in crypto credit markets. In July, Block Earner launched Bitcoin-backed home loans in Australia, providing buyers with a means to leverage their BTC holdings for up to half of a property’s value, amidst rising housing prices in the country.

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